Long-lasting, specific immunologic unresponsiveness associated with cryptococcal meningitis.
نویسندگان
چکیده
منابع مشابه
HIV-associated cryptococcal meningitis.
While the incidence of cryptococccal meningitis in the developed world has declined with widespread, early antiretroviral therapy (ART), cryptococcal disease remains a major opportunistic infection and leading cause of mortality in patients infected with HIV in much of the developing world. Most HIV-related cases are caused by Cryptococcus neoformans var. grubii (serotype A), while var. neoform...
متن کاملCryptococcal intracerebral mass lesions associated with cryptococcal meningitis.
12 patients with cryptococcal intracerebral mass lesions associated with cryptococcal meningitis are reported. There were 6 males and 6 females with a mean age of 41 years. Most of them presented with symptoms and signs of meningitis initially without focal neurological signs. Computed tomography revealed single or multiple, well or poorly marginated hypodense lesions without perilesional edema...
متن کاملImmune correlates of HIV-associated cryptococcal meningitis
1 Division of Allergy and Infectious Diseases, University of Washington School of Medicine, Seattle, Washington, United States of America, 2 Department of Epidemiology, University of Washington School of Public Health, Seattle, Washington, United States of America, 3 Liverpool School of Tropical Medicine, Liverpool, United Kingdom, 4 Institute for Infection and Immunity, St George’s, University...
متن کاملAdjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis.
BACKGROUND Cryptococcal meningitis associated with human immunodeficiency virus (HIV) infection causes more than 600,000 deaths each year worldwide. Treatment has changed little in 20 years, and there are no imminent new anticryptococcal agents. The use of adjuvant glucocorticoids reduces mortality among patients with other forms of meningitis in some populations, but their use is untested in p...
متن کاملCryptococcal Meningitis
Virulence probably plays a relatively small role in the outcome of this infection: the crucial factor is the immune status of the host. The most serious infections usually develop, in fact, in patients with defective cell-mediated immunity, for example those with AIDS, organ transplantation, reticuloendothelial malignancy, corticosteroid treatment and sarcoidosis, but not in subjects with neutr...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1982
ISSN: 0021-9738
DOI: 10.1172/jci110555